Modificări ale metabolismului lipidic la pacienții diabetici-studiu pilot | [Changes in lipid metabolism in diabetic patients - pilot study]
نویسندگان
چکیده
Introduction: Diabetes is a group of metabolic disorders characterized by high blood sugar levels. The etiology represented complex interaction between genetic and environmental factors. Metabolic contribute to the pathogenesis insulin resistance diabetes mellitus development. insulin`s action in adipocytes associated with an increase lipolysis concentration free fatty acids. Stress plays significant role diabetes`s affects disease`s evolution (debut, progression, chronicity) through behavior changes. An analysis was performed based on smoker status includes other information about patients' comorbidities. study descriptive retrospective, analyzing 47 patients inclusion criteria (patients type 2 diabetes, people determinations lipid profile glucose, females males, with/without BMI values, existing pathologies, hereditary antecedents. Objective. This paper aims highlight panel changes mellitus, order understand challenges disease management, particularities each. Discussions: has negative impact terms it generates (treatment disruption/diet, incorrect monitoring treatment). Smoking another factor that ability influence level mechanisms favored it. Conclusions: been shown be higher risk dyslipidemia. It hard quantify stress also determine its diabetes` etiology. itself could source due management requires-especially treatment. Rezumat Introducere: Diabetul zaharat (DZ) reprezintă un grup de boli metabolice cu o caracteristică definitoriehiperglicemia. Tipologia acestuia are drept etiologie interacțiune complexă între factorii genetici și cei mediu. Tulburările la persoanele obeze contribuie patogeneza rezistenței insulină dezvoltarea DZ tip 2. Acțiunea insulinei în adipocite este asociată creșterea lipolizei concentrației acizilor grași liberi care conduc depunerea grăsimi ficat mușchii scheletici. Stresul rol semnificativ etiologia afectează evoluția bolii progresie cronicizare) prin modificările comportament. O analiză fost realizată funcție statusul fumător cuprinde alte informații despre comorbiditățile bolnavilor. Studiul realizat descriptiv retrospectiv, fiind analizați pacienți pe baza criteriilor includere (pacienți 2, persoane determinări ale profilului lipidic glicemiei, gen feminin masculin, pacienții cu/ fără valori IMC, patologii existente, antecedente heredocolaterale. Scop/Obiectiv: Lucrarea își propune să evidențieze lipic DZ, scopul înțelege provocările managementul bolii, provocări reprezentate particularitățile fiecăruia. Discuții: negativ asupra evoluției prisma comportamentului îl determină (necomplianța tratament/regim alimentar, monitorizarea insuficientă/incorectă tratamentului). Un alt capacitatea influența atât profilul cât cel glicemic fumatul mecanismele fiziopatologice favorizate acesta. Concluzii: S-a observat că stresul asociat risc crescut al apariției diabetului dislipidemiilor, special femei. Este dificil se cuantifice nivelul stres afirme exactitate rolul său diabetului, multe ori însuși boala constituie sursă necesită – mai ales din punct vedere terapeutic.
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ژورنال
عنوان ژورنال: Jurnal medical bra?ovean
سال: 2022
ISSN: ['1841-0782', '2247-4706']
DOI: https://doi.org/10.31926/jmb.2021.2.10